实验室最新动态请参阅课题组主页：http://bionano.chem.hust.edu.cn/

2021-2022年招收具有合成生物学、人工酶、非天然氨基酸表达、生物工程、微生物学方面研究背景的博士后2-3名。详细信息请参见：http://muchong.com/html/201907/13536956.html

个人介绍

吴钰周，18luck新利电竞 化学与化工学院教授，博士生导师。先后于浙江大学、新加坡国立大学、和德国乌尔姆大学获得学士、硕士和博士学位。2013年5月-2016年9月先后担任德国乌尔姆大学和马普高分子研究所课题组长，2016年9月起任18luck新利电竞 化学与化工学院教授，兼任马普高分子研究所课题组长，2019年任国家重点研发计划青年项目首席科学家。2019年吴钰周教授课题组被遴选为德国马普学会国际伙伴研究小组。

吴钰周教授主要从事功能生物大分子材料领域的研究，主要方向包括蛋白质及核酸衍生的智能生物纳米材料、纳米医药及靶向药物载体、DNA折纸材料与纳米医学和人工酶合成生物学。研究成果已在国际权威期刊发表论文60余篇，第一及通讯作者在包括Nature. J. Am. Chem. Soc.，Angew. Chem. Int. Ed., Acc. Chem. Res., Adv. Func. Mater.，ACS Nano, Nano Lett.等期刊发表论文30余篇，多篇文章被选做期刊封面，并被Nature等期刊大篇幅引用评述。

吴钰周教授参与了欧盟地平线2020计划框架下的“个性化健康与治疗（PHC）”大型国际合作项目（子课题共同负责人）、德国巴登符腾堡州基金会中德合作项目（项目共同负责人）、德国科学基金会（DFG）重大专项（SFB1279）（子课题共同负责人），乌尔姆大学Forschungsbonus 课题（项目负责人），与德国乌尔姆大学医学院及德国知名药企Merck Pharmaceuticals 公司合作紧密合作，研究成果多次被体Südwest Presse等德国知名媒报道，受邀在SICC, IUPAC Macro, China Nano,中国化学会学术年会等国际国内学术会议上做邀请报告，并担任Materials等期刊的客座编辑和ACS Nano, Small, Nanoscale等期刊的审稿人，获得了乌尔姆大学优秀博士论文奖，Forschungsbonus，Reaxys PhD Prize提名奖等荣誉。

目前主持在研项目:

1）国家自然科学基金面上项目（DNA折纸表面原位聚合构建高精度表面亚结构及其生物效应研究，2021-2024）

2）国家重点研发计划“合成生物学”重点专项（非金属活性中心人工酶的构筑及手性生物合成研究， 2019-2024）

3）湖北省重点研发计划（高密度DNA信息存储方法和技术研究，2022-2023）

研究方向

1）人工酶合成生物学

2) DNA折纸术

3) 复合生物高分子材料

4) 纳米医药及靶向药物载体

5) 智能生物纳米材料

发表论文

87. Ningning Sun, Jianjian Huang, Junyi Qian, Taiping Zhou, Juan Guo, Langyu Tang, Wentao Zhang, Yaming Deng, Weining Zhao, Guojiao Wu, Rongzhen Liao, Xi Chen*, Fangrui Zhong* & Yuzhou Wu*, Enantioselective [2+2]-cycloadditions with triplet photoenzymes, Nature, 2022, https://doi.org/10.1038/s41586-022-05342-4

86. Longjie Li, Kejun Dong, Xinyu Wange, Meizhou Zhang, Jun Li, Andreas K. Nussler, Xianjin Xiao, Hongbo Wang* and Yuzhou Wu*, DNA origami‐based nano‐hunter enriches low‐abundance point mutations by targeting wild-type gene segments. Chinese Chemical Letters, 2022, 33, 2052.

85.  Huaibin Yu, Shuangshuang Wang, Jianjian Huang, Yu Fu, Manfred Wagner, Tanja Weil, Fangrui Zhong, Weining Zhao*, and Yuzhou Wu*, Light-Controlled Traceless Protein Labeling via Decaging Thio-o-naphthoquinone Methide Chemistry, Org. Lett. 2022, 24, 6816.

84. Yiwei Shi, Xuemei Xu, Huaibin Yu, Zian Lin, Honghua Zuo, and Yuzhou Wu*, Defined positive charge patterns created on DNA nanostructures determine cellular uptake efficiency. Nano Lett. 2022, 22, 5330.

83. Jingyang Qin,Tong Zhou,Taiping Zhou,Langyu Tang,Honghua Zuo,Huaibin Yu,Guojiao Wu,Yuzhou Wu,Rong-Zhen Liao*,Fangrui Zhong*,Catalytic Atroposelective Electrophilic Amination of Indoles, Angew. Chem. Int. Ed. 2022, e202205159.

82. Huaibin Yu,Jiayi Feng,Fangrui Zhong,Yuzhou Wu*, Chemical Modification for the “Off-/On” Regulation ofEnzyme Activity. Macromol. Rapid Commun.2022, 43, 2200195.

81. Qiuyue Ding, Tingfang Sun, Weijie Su, Xirui Jing, Bing Ye, Yanlin Su, Lian Zeng,Yanzhen Qu, Xu Yang, Yuzhou Wu, Zhiqiang Luo, and Xiaodong Guo*, Bioinspired Multifunctional Black Phosphorus Hydrogelwith Antibacterial and Antioxidant Properties: A StepwiseCountermeasure for Diabetic Skin Wound Healing, Adv. Healthcare Mater. 2022, 11, 2102791.

80. Boyang Hu, Ruijie Liu, Qingyue Liu, Zi’an Lin, Yiwei Shi, Jun Li, Lijun Wang, Longjie Li,* Xianjin Xiao* and Yuzhou Wu*,  Engineering surface patterns on nanoparticles: new insights into nano-bio interactions. J. Mater. Chem. B, 2022, 10, 2357.

79. Yaming Deng,  Quan Zhou, Yuzhou Wu, Xi Chen*, Fangrui Zhong*, Properties and Mechanisms of Flavin-Dependent Monooxygenases and Their Applications in Natural Product Synthesis.  Int. J. Mol. Sci. 2022, 23, 2622.

78. Liandong Feng, Li Yang, Longjie Li, Junying Xiao, Nana Bie, Chao Xu, Jun Zhou, Hongmei Liu, Lu Gan, Yuzhou Wu*, Programmed albumin nanoparticles regulate immunosuppressive pivot to potentiate checkpoint blockade cancer immunotherapy, Nano Research, 2022, 15, 593-602.

77. Liandong Feng, Shanshan Wu, and Yuzhou Wu*, Intracellular bottom-up Synthesis of Ultrasmall CuS Nanodots in Cancer Cells for Simultaneous Photothermal Therapy and COX-2 Inactivation, Adv. Funct. Mater., 2021, 31, 2101297

76. Colette J. Whitfield, Meizhou Zhang, Pia Winterwerber, Yuzhou Wu*, David Y. W. Ng*, and Tanja Weil* Functional DNA–Polymer Conjugates, Chem. Rev. 2021,  121, 11030.

75. Yu Fu,# Jian Huang,# Yuzhou Wu,* Xiaohong Liu,* Fangrui Zhong,* and Jiangyun Wang*, “Biocatalytic Cross-Coupling of Aryl Halides with a Genetically Engineered Photosensitizer Artificial Dehalogenase” J. Am. Chem. Soc. 2021, 143, 617.

74. Xunbo Lu, Yulong Bai, Jingyang Qin, Nan Wang, Yuzhou Wu,* and Fangrui Zhong*, “Alleviating Catalyst Decay Enables Efficient Intermolecular C(sp3)−H Amination under Mechanochemical Conditions” ACS Sustainable Chem. Eng, 2021, 9, 1684-1691.

73. Shengze Xiao Long Mao, Junying Xiao, Yuzhou Wu, Hongmei Liu*, Eur. J. Pharmacol. 2021, 902, 174120.

72. Jin Liu,  Liandong Feng, Yuzhou Wu*, Enzymatically synthesised MnO2 nanoparticles for efficient near-infrared photothermal therapy and dual-responsive magnetic resonance imaging, Nanoscale, 2021, 13, 11093.

71. Jin Liu, Meizhou Zhang, Yuzhou Wu*, In situ synthesis of fluorescent polydopamine on biogenic MnO2 nanoparticles as stimuli responsive multifunctional theranostics, Biomater. Sci., 2021, 9, 5897.

70. Guang-Jing Feng, Shuang-Shuang Wang, Jian Lv, Tao Luo, Yuzhou Wu,  Hai Dong*, Improved Synthesis of 1-Glycosyl Thioacetates and Its Application in the Synthesis of Thioglucoside Gliflozin Analogues, Eur. J. Org. Chem, 2021, 2940.

69. Junying Xiao, Hui Cao, Siyu Guo, Shengze Xiao, Na Li, Min Li, Yuzhou Wu, Hongmei Liu*, Long-term administration of low-dose selenium nanoparticles with different sizes aggravated atherosclerotic lesions and exhibited toxicity in apolipoprotein E-deficient mice, Chem. Biol. Interact, 2021, 247, 109601

68. Meizhou Zhang, Shuangshuang Wang, Longjie Li, Mengran Li, Xinyi Cheng, Yiwei Shi, Yuzhou Wu*, Digital Numbers Constructed by Fine Patterned Polydopamine on DNA Templates, Macromol Rapid Commun, 2021, 42, e2100441.

67. Shanshan Wu, Yi Chen,  Xiaodong Guo, Yuzhou Wu*, Collagen mineralization and its applications in hard tissue repair, Mater. Chem. Front., 2021, 5, 7071-7087.

66. Weiguo Qiao, Teng Ma, Shuangshuang Wang, Longjie Li, Miao Liu, Hao Jiang, Yuzhou Wu, Jintao Zhu, Zhong'an Li*, Adv. Funct. Mater. 2021, 31, 2105452.

65. Tai-Ping Zhou, Fangrui Zhong,* Yuzhou Wu and Rong-Zhen Liao,* “Regioselectivity and stereoselectivity of intramolecular [2 + 2] photocycloaddition catalyzed by chiral thioxanthone: a quantum chemical study”, Org. Biomol. Chem. 2021, 19, 1532-1540

64. So Yeon Ahn, Jin Liu, Srivithya Vellampatti, Yuzhou Wu*, Soong Ho Um* DNA Transformations for Diagnosis and Therapy, Adv. Funct. Mater. 2021, 31, 2008279.

63. Qianqian Liu, Yu-Jin Kim, Gwang-Bum Im, Jintao Zhu, Yuzhou Wu, Yijing Liu,* Suk Ho Bhang* Inorganic Nanoparticles Applied as Functional Therapeutics, Adv. Funct. Mater. 2021, 31, 2008171.

62. Shanshan Wu, Meizhou Zhang , Jie Song, Stefan Weber, Xiaoguo Liu, Chunhai Fan, and Yuzhou Wu*, Fine Customization of Calcium Phosphate Nanostructures with Site-Specific Modification by DNA Templated Mineralization, ACS Nano 2021, 15, 1555.

61. Wanying Ye, Haijie Han, Huan Li, Qiao Jin, *, Yuzhou Wu, Sabyasachi Chakrabortty, Tanja Weil, Jian Ji, Polymer coated nanodiamonds as gemcitabine prodrug with enzymatic sensitivity for pancreatic cancer treatment, Progress in Natural Science: Materials International, 2020, 30, 711.

60. Longjie Li, ‡ Wenkai Zhang,‡ Xiaofeng Tang, Zejian Li, Yuzhou Wu,* Xianjin Xiao* Fine and bidirectional regulation of toehold-mediated DNA strand displacement by a wedge-like DNA tool, Chem. Commun., 2020, 56, 8794.

59. Adnan Bashir, Honghua Zuo, Xunbo Lu, Yuzhou Wu, Fangrui Zhong*, Harnessing structurally unbiased ortho-benzoquinone monoimine for biomimetic oxidative [4+2] cycloaddition with enamines, Chem. Commun., 2020, 56, 5965.

58. Ahmed El-Harairy,* Mennatallah Shaheen, Jun Li, Yuzhou Wu, Minghao Li, Yanlong Gu, Synthesis of α-indolylacrylates as potential anticancer agents using a Bronsted acid ionic liquid catalyst and the butyl acetate solvent. RSC Adv., 2020, 10, 13507.

57. Juan Guo, Huan Guo, Jin Liu*, Fangrui Zhong and Yuzhou Wu*, Manganese(II) Oxidizing Bacteria as Whole-Cell Catalyst for beta -Keto Ester Oxidation, Int. J. Mol. Sci. 2020, 21, 1709.

56. Yuan Zhuang, Longjie Li, Liandong Feng, Shuangshuang Wang, Huimin Su, Haijuan Liu, Hongmei Liu* and Yuzhou Wu*, Mitochondrion-targeted selenium nanoparticles enhance reactive oxygen species-mediated cell death, Nanoscale, 2020, 12, 1389.

55. Xuemei Xu, Pia Winterwerber, David Ng, Yuzhou Wu*, DNA-Programmed Chemical Synthesis of Polymers and Inorganic Nanomaterials, Top. Curr. Chem. 2020, 378, 31.

54. Jessica Wagner, Longjie Li, Johanna Simon, Lea Krutzke, Katharina Landfester, Volker Mail-nder, Klaus Mgllen, David Y. W. Ng,* Yuzhou Wu,* and Tanja Weil* Amphiphilic Polyphenylene Dendron Conjugates for Surface Remodeling of Adenovirus 5, Angew. Chem. Int. Ed. 2020, 59, 5712.

53. Yuzhou Wu*, Longjie Li, Larissa Frank, Jessica Wagner, Patrizia Andreozzi, Brenton Hammer, Marco D’Alicarnasso, Maria Pelliccia, Weina Liu, Sabyasachi Chakrabortty, Silke Krol, Johanna, Simon, Katharina Landfester, Seah Ling Kuan, Francesco Stellacci, Klaus Müllen, Florian Kreppel*, Tanja Weil*, Patchy Amphiphilic Dendrimers Bind Adenovirus and Control Its Host Interactions and in Vivo Distribution, ACS Nano, 2019, 13, 8749.

52. Xuemei Xu, Shiqi Fang, Yuan Zhuang, Shanshan Wu, Qingling Pan, Longjie Li, Xiaohui Wang, Xueqing Sun, Bifeng Liu, Yuzhou Wu*, Cationic Albumin Encapsulated DNA Origami for Enhanced Cellular Transfection and Stability, Materials, 2019, 12, 949.

51. Yan Li, Longjie Li, Xunbo Lu, Yulong Bai, Yufan Wang, Yuzhou Wu* and Fangrui Zhong* "Bioinspired radical cyclization of tryptamines: synthesis of peroxypyrroloindolenines as potential anti-cancer agents" Chem. Commun., 2019, 55, 63.

50. Qile Yu, Yu Fu, Jianjian Huang, Jingyang Qin, Honghua Zuo, Yuzhou Wu*, Fangrui Zhong*, "Enantioselective Oxidative Phenol-Indole [3+ 2] Coupling Enabled by Biomimetic Mn (III)/Brønsted Acid Relay Catalysis" ACS Catal. 2019, 9, 7285

49.  Tanghui Duan, Liu He, Yu Tokura, Xin Liu, Yuzhou Wu*, Zhengshuang Shi*. Construction of tunable peptide nucleic acid junctions. Chem. Commun., 2018, 54, 2846.

48. Yu Tokura^#, Sean Harvey^#, Chaojian Chen, Yuzhou Wu*, David Y. W. Ng*, Tanja Weil*. Fabrication of Defined Polydopamine Nanostructures by DNA Origami-Templated Polymerization. Angew. Chem. Int. Ed. 2018, 57, 1587 –1591.

47.  Yu Tokura, Sean Harvey, Yuzhou Wu, * David Y. W. Ng *,Tanja Weil *.Polymer tube nanoreactors via DNA-origami templated synthesis. Chem. Commun., 2018, 54, 2808.

46. Weina Liu, Felix Boldt, Yu Tokura, Tao Wang, Bikram Keshari Agrawalla, Yuzhou Wu* and Tanja Weil*, Encoding function into polypeptide-oligonucleotide precision biopolymers, Chem. Commun., 2018, 54, 11797-11800.

45. Sylvia Schmid,* Jasmina Gačanin, Yuzhou Wu, Tanja Weilbd, Peter Bäuerlea. Synthesis and bioconjugation of first alkynylated poly(dithieno[3,2-b:2′,3′-d]pyrrole)s. Polym. Chem., 2017, 8, 7113-7118.

44.  David Y. W. Ng*, Roman Vill, Yuzhou Wu, Kaloian Koynov, Yu Tokura, Weina Liu, Susanne Sihler, Andreas Kreyes, Sandra Ritz, Holger Barth, Ulrich Ziener*, Tanja Weil*. Directing intracellular supramolecular assembly with N-heteroaromatic quaterthiophene analogues. Nature Communications, 2017, 8: 1850.

43. Jasmina Gačanin, Anna Kovtun, Stephan Fischer, Victoria Schwager, Johanna Quambusch, Seah Ling Kuan, Weina Liu, Felix Boldt, Chuang Li, Zhongqiang Yang, Dongsheng Liu, Yuzhou Wu*, Holger Barth*, Anita Ignatius*. Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein–DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity. Adv. Healthcare Mater. 2017, 6, 17.

42.  Brenton A. G. Hammer, Yuzhou Wu, Stephan Fischer, Weina Liu, Tanja Weil*, Klaus Müllen*. Controlling Cellular Uptake and Toxicity of Polyphenylene Dendrimers by Chemical Functionalization. Chembiochem, 2017, 18, 960-964.

41. Zhi Zuo, Tatiana Syrovets, Yuzhou Wu, Susanne Hafner, Ina Vernikouskaya, Weina Liu, Genshan Ma, Tanja Weil, Thomas Simmet, Volker Rasche*. The CAM cancer xenograft as a model for initial evaluation of MR labelled compounds. Scientific Reports, 2017, 7, 4669

40. Sabyasachi Chakrabortty, Miguel Sison, Yuzhou Wu, Anita Ladenburger, Goutam Pramanik, Johannes Biskupek, Jerome Extermann, Ute Kaiser, Theo Lasser, Tanja Weil*. NIR-emitting and photo-thermal active nanogold as mitochondria-specific probes. Biomater. Sci., 2017, 5, 966-971.

39. Yuzhou Wu, Tanja Weil, Nanodiamonds for Biological Applications, Phys. Sci. Rev., 2017, DOI: 10.1515/9783110284645-009.

38. Beatriz Pelaz, Christoph Alexiou, Ramón A Alvarez-Puebla, … Yuzhou Wu, …Wolfgang J. Parak*, Diverse Applications of Nanomedicine, ACS Nano, 2017, 11, 2313-2381.

37. Yuzhou Wu*, Fedor Jelezko, Martin Plenio, Tanja Weil*, Diamond Quantum Devices in Biology, Angew. Chem. Int. Ed., 2016, 55, 6586-6598.

36. Yu Tokura^#, Yanyan Jiang^#, Alexander Welle, Martina H Stenzel, Katarzyna Krzemien, Jens Michaelis, Christopher Barner-Kowollik, Yuzhou Wu*, Tanja Weil*, Bottom-up Fabrication of Nanopatterned Polymers on DNA Origami Nanotile by In-situ Atom Transfer Radical polymerization. Angew. Chem. Int. Ed. 2016, 55, 5692-5697.

35. Weina Liu, Boris Naydenov, Sabyasachi Chakrabortty, Bettina Wuensch, Kristina Hübner, Sandra Ritz, Helmut Cölfen, Holger Barth, Kaloian Koynov, Haoyuan Qi, Robert Leiter, Rolf Reuter, Jörg Wrachtrup, Felix Boldt, Jonas Scheuer, Ute Kaiser, Miguel Sison, Theo Lasser, Philip Tinnefeld, Fedor Jelezko, Paul Walther, Yuzhou Wu*, and Tanja Weil*. Fluorescent Nanodiamond–Gold Hybrid Particles for Multimodal Optical and Electron Microscopy Cellular Imaging. Nano Lett., 2016, 16, 6236–6244.

34. Sylvia Schmid*, David. Y. W. Ng, Elena. Mena-Osteritz, Yuzhou Wu, Tanja Weil, Peter Bäuerle, Self-assembling oligothiophene–bolaamphiphiles for loading and controlled release of doxorubicin into living cells. Chem. Commun., 2016, 52, 3235-3238.

33. Christiane Seidler, David. Y. W. Ng, Yuzhou Wu and Tanja Weil*. pH responsive supramolecular core-shell protein hybrids, Supramolecular Chemistry, 2016, 28, 742-746.

32.  Seah Ling Kuan, Christina Förtsch, David Y. W. Ng, Stephan Fischer, Yu Tokura, Weina Liu, Yuzhou Wu, Kaloian Koynov, Holger Barth, Tanja Weil*, A supramolecular approach toward bioinspired PAMAM-dendronized fusion toxins, Macromol. Biosci. 2016, 16, 803−810.

31. Tao Wang^#, Andreas Riegger^#, Markus Lamla, Sebastian Wiese, Patrick Oeckl, Markus Otto, Yuzhou Wu, Stephan Fischer, Holger Barth, Seah Ling Kuan, Tanja Weil*, Water-soluble allyl sulfones for dual site-specific labelling of proteins and cyclic peptides, Chem. Sci., 2016, 7, 3234-3239.

30. Felix Boldt, Weina Liu, Yuzhou Wu*, Tanja Weil*. Converting Human Proteins into Precision Polymer Therapeutics. Curr Pharm Des., 2016, 22, 2866-2872.

29. David Palesch, Felix Boldt, Janis A. Müller, Klaus Eisele, Christina M. Stürzel, Yuzhou Wu*, Jan Münch*, Tanja Weil*. PEGylated cationic serum albumin to boost retroviral gene transfer. ChemBioChem, 2016, 17, 1504-1508.

28. Tao Wang, Yuzhou Wu, Seah Ling Kuan, Oliver Dumele, Markus Lamla, David Y. W. Ng, Matthias Arzt, Jessica Thomas, Jan. O. Mueller, Christopher Barner-Kowollik*, Tanja Weil*, A Disulfide Intercalator Toolbox for Site-Directed Polypeptide Modification, Chemistry – a European Journal, 2015, 21, 228-238.

27. Tao Wang, Yuzhou Wu, MarkusLamla, David Y. W.Ng,* Sven Rau* and TanjaWeil*, Receptor Selective Ruthenium-Somatostatin Photosensitizer for Cancer Targeted Photodynamic Applications, Chem. Commun. 2015, 51, 12552-12555.

26. Tao Zhang, Yuzhou Wu, Alexander Högele*, Tanja Weil* and Tim Liedl*, DNA-based self-assembly of fluorescent nanodiamonds, J. Am. Chem. Soc., 2015, 31, 9776–9779.

25. Yuzhou Wu*, Fedor Jelezko*, Tanja Weil*, Programmable Biopolymers for Advancing Biomedical Applications of Fluorescent Nanodiamonds. Adv. Funct. Mater. 2015, 25, 6576–6585.

24. Yuzhou Wu, David Yuen Wah Ng, Seah Ling Kuan, Tanja Weil*, “Protein-Polymer Therapeutics – A Macromolecular Perspective”, Biomaterials Science, 2015, 3, 214-230.

23. René Stangenberg^#, Yuzhou Wu^#, Seah Ling Kuan, Dennis Kurzbach, Dariush Hinderberger, Jana Hedrich, Malin Insa Preiß, Heiko J. Luhmann, Tanja Weil* and Klaus Müllen*, A Polyphenylene Dendrimer Drug Transporter with Precisely Positioned Amphiphilic Surface Patches. Adv. Healthcare Mater. 2015, 4, 377–384.

22. Yuzhou Wu*, Chuang Li, Felix Boldt, Christina Förtsch, Holger Barth, Yanran Wang, Seah Ling Kuan, Thuy Tam Tran, Viktoria Mikhalevich, Zhongqiang Yang, Dongsheng Liu*, Tanja Weil*. Programmable protein–DNA hybrid hydrogels for the immobilization and release of functional proteins. Chem. Commun., 2014, 50, 14620-14622.

21. David Yuen Wah Ng^#, Yuzhou Wu^#, Seah Ling Kuan and Tanja Weil*. Programming Supramolecular Biohybrids as Precision Therapeutics. Acc. Chem. Res., 2014, 47, 3471-3480. (#Shared first authorship).

20. Chuang Li, Ping Chen, Yu Shao, Xu Zhou, Yuzhou Wu, Zhongqiang Yang, Zhibo Li, Tanja Weil, Dongsheng Liu*, A writable polypeptide-DNA hydrogel with rationally designed multi-modification sites, Small, 2014, 11, 1138-1143.

19. Tao Wang, David Y. W. Ng, Yuzhou Wu, Jessica Thomas, Thuy TamTran and Tanja Weil*. Bis-sulfide bioconjugates for glutathione triggered tumor responsive drug release. Chem. Commun., 2014, 50, 1116-1118.

18. David Y. W. Ng, Matthias Arzt, Yuzhou Wu, Seah Ling Kuan, Markus Lamla, Tanja Weil*. Constructing Hybrid Protein Zymogens through Protective Dendritic Assembly. Angew. Chem. Int. Ed. 2014, 53, 324-328.

17. Christoph Meier, Yuzhou Wu, Goutam Pramanik, Tanja Weil*. Self-Assembly of High Molecular Weight Polypeptide Copolymers Studied via Diffusion Limited Aggregation. Biomacromolecules, 2014, 15, 219-227.

16. David Y. W. Ng, Jörg Fahrer, Yuzhou Wu, Klaus Eisele, Seah Ling Kuan, Holger Barth*, Tanja Weil*. Efficient Delivery of P53 and Cytochrome C by Supramolecular Assembly of a Dendritic Multi-Domain Delivery System. Adv. Healthcare Mater., 2014, 2, 1620-1629.

15. Yuzhou Wu, Susann Ihme, Michaela Feuring-Buske, Seah Ling Kuan, Klaus Eisele, Markus Lamla, Yanran Wang, Christian Buske, Tanja Weil*. A Core-shell Albumin Copolymer Nanotransporter for High Capacity Loading and Two-step Release of Doxorubicin with Enhanced Anti‐Leukemia Activity. Adv. Healthcare Mater. 2013, 2, 884–894.

14. Diego Pesce#, Yuzhou Wu#, Anke Kolbe, Tanja Weil* and Andreas Herrmann*. Enhancing Cellular Uptake of GFP via Unfolded Supercharged Protein Tags. Biomaterials, 2013, 34, 4360. (#Shared first authorship)

13. Seah Ling Kuan, David Y. W. Ng, Yuzhou Wu, Christina Förtsch, Holger Barth, Mikheil Doroshenko, Kaloian Koynov, Christoph Meier, Tanja Weil*.pH Responsive Janus-like Supramolecular Fusion Proteins for Functional Protein Delivery. J. Am. Chem. Soc. 2013, 135, 17254–17257.

12. Jana Hedrich, Yuzhou Wu, Manfred Schmidt. Polymer Complexes in Biological Applications. Adv. Polym. Sci. 2013, doi: 10.1007/12_2013_229. (Book Chapter).

11. Tao Wang, Yuzhou Wu, Tanja Weil*. A Versatile and Orthogonal Approach for the Cross-Conjugation of DNA, Proteins and Peptides via the pH Switch. Chem. Sci., 2013, 4, 1889-1894.

10. Seah Ling Kuan, Yuzhou Wu, Tanja Weil*. Precision Biopolymers from Protein Precursors for Biomedical Applications. Macromol Rapid Commun., 2013, 34, 380.

9. Seah Ling Kuan, Bettina Stöckle, David Y.W. Ng, Yuzhou Wu, Mikheil Doroshenko, Jörg Reichenwallner, Kaloian Koynov, Dariush Hinderberger, Klaus Müllen, Tanja Weil*. Dendronized Albumin Biohybrids as Efficient Core-Shell Doxorubicin Delivery Systems, Biomacromolecules, 2013, 14, 367–376.

8. Yuzhou Wu, Klaus Eisele, Mikheil Doroshenko, Gerardo Algara-Siller, Ute Kaiser, Kaloian Koynov, Tanja Weil*. A Quantum Dot Photoswitch for DNA Detection, Gene Transfection, and Live-Cell Imaging. Small, 2012, 8, 3465–3475. (Cover article)

7. Yuzhou Wu, Goutam Pramanik, Klaus Eisele, Tanja Weil*. Convenient Approach to Polypeptide Copolymers Derived from Native Proteins. Biomacromolecules, 2012, 13, 1890-1898.

6. Yuzhou Wu, Tao Wang, David Y.W. Ng, Tanja Weil*. Multifunctional Polypeptide-PEO Nanoreactors via the Hydrophobic Switch. Macromol. Rapid Commun., 2012, 33, 1474-1481.

5. Yuzhou Wu, Tanja Weil*. An Efficient Approach for Preparing Giant Polypeptide Triblock Copolymers by Protein Dimerization. Macromol. Rapid Commun., 2012, 33, 1304-1309.

4. Yuzhou Wu, Kai Shih Er, Arvind Ramanathan, Subhash Vasudevan, Tanja Weil*. Nano-sized Albumin-copolymer Micelles for Efficient Doxorubicin Delivery. Biointerphases. 2012, 7, 5.

3.Yasar Akdogan, Yuzhou Wu, Klaus Eisele, Manuela Schaz, Tanja Weil* and Dariush Hinderberger*. Host-Guest Interactions in Polycationic Human Serum Albumin Bioconjugates. Soft Matter, 2012, 8, 11106-11114.

2. Tanja Weil, Goutam Pramanik, Yuzhou Wu. Protein-based copolymers for bioimaging and drug delivery applications. Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 2011, 52, no page given.

1. Yuzhou Wu, Sabyasachi Chakrabortty, Radu A. Gropeanu, Joerg Wilhelmi, Yang Xu, Kai Shih Er, Seah Ling Kuan, Kaloian Koynov, Yinthai Chan* and Tanja Weil*. pH-Responsive Quantum Dots via an Albumin Polymer Surface Coating, J. Am. Chem. Soc., 2010, 51, 786-787.