樊锦轩，助理研究员，硕士生导师。主要从事生物医用材料、抗肿瘤细胞疗法等相关研究。近年来发表SCI期刊论文50余篇，其中以第一或通讯作者身份发表SCI论文24篇，包括Adv Mater, Biomaterials, Nano Lett, Adv Funct Mater 等权威期刊。申请中国发明专利4项，授权2项。先后主持国家自然科学基金青年基金，中国博士后（站前）特别资助，中国博士后面上项目等在内的多项国家级、省部级课题。参与国家自然科学基金重点项目、重大项目、面上项目等在内的多项课题。现任《Advanced Biotechnology》青年编委，受邀担任Adv Mater、Biomaterials、Small、CEJ等专业期刊审稿人。

研究方向：

      1. 基于工程化细胞的抗肿瘤免疫疗法

      2. 纳米生物传感与疾病诊疗

科研项目：

主持：1. 国家自然基金青年项目

          2. 中国博士后特别资助项目（站前）

          3. 中国博士后面上项目

          4. 湖北省创新研究岗位

          5. 白求恩菁锐科研发展基金

          6. 生物医用高分子材料教育部重点实验室开放基金

参与：1. 国家自然科学基金重点项目（2项）

          2. 国家自然科学基金重大项目

代表性论文：

1. R.Y. Zhang, K. Cheng, Z.Y. Huang, X.S. Zhang, Y. Li, X. Sun, X.Q. Yang, Y.G. Hu, X.L. Hou, B. Liu, W. Chen, J.X. Fan*, Y.D. Zhao*, M1 macrophage-derived exosome for reprograming M2 macrophages and combining endogenous NO gas therapy with enhanced photodynamic synergistic therapy in colorectal cancer. J. Colloid Interf. Sci. 2024, 654, 612.

2. H. Yang, X.S. Zhang, K. Cheng, B. Liu, W. Chen, J.X. Fan*, Y.D. Zhao*, One-step detection of glutathione based on MnO₂ nanosheet and pregnancy test strip. Sensor. Actuat. B-Chem. 2024, 410, 135652.

3. L. Zhang, J.M. Fu, L.B. Song, K. Cheng, F. Zhang, W.H. Tan, J.X. Fan*, Y.D. Zhao*, Ultrasmall Bi/Cu coordination polymer combined with glucose oxidase for tumor enhanced chemo-dynamic therapy by starvation and photothermal treatment. Adv. Healthc. Mater. 2023, 2302264. 

4. Y.J. Tang, K. Cheng, P.J. Zhang, Y.F. He, M.W. Ma, W.M. Su, G.P. Wang*, J.X. Fan*, Y.D. Zhao*, A near-infrared light responsive temperature-sensing switch in a submicro-channel heterogeneous membrane, J. Mater. Chem. A 2023, 11, 18765.

5. X.L. Lei, K. Cheng, Y.G. Hu, Y. Li, X.L. Hou, F. Zhang, L.F. Tan, Z.T. Zhong, J.H. Wang, J.X. Fan*, Y.D. Zhao*, Gelatinase-responsive biodegradable targeted microneedle patch for abscess wound treatment of S. aureus infection, Int. J. Biol. Macromol. 2023, 253, 8, 127548.

6. J.X. Fan‡, Z.B. Hu‡, H.Y. Gu, W.Q. Qu, W. Li, B.W. Qi, A.X. Yu*, X.Z. Zhang*, Tumor cell membrane remodeling with universal ligand for CAR-T cells to inhibit solid tumors. Sci. China Chem. 2023, 66, 3223.

7. J.X. Fan‡, M.Y. Peng‡, H. W., H.R. Zheng, Z.L. Liu, C.X. Li, X.N. Wang, X.H. Liu, S.X. Cheng, X.Z. Zhang*, Engineered bacterial bioreactor for tumor therapy via fenton-like reaction with localized H₂O₂ generation. Adv. Mater. 2019, 1808278 (ESI Highly Cited Paper, Cover Paper)

8. D.W. Zheng‡, J.X. Fan‡, X.H. Liu, X. Dong, P. Pan, L. Xu, X.Z. Zhang*, A simply modified lymphocyte for systematic cancer therapy. Adv. Mater. 2018, 1801622.

9. J.X. Fan‡, X.H. Liu‡, X.N. Wang, M.T. Niu, Q.W. Chen, D.W. Zheng, J.S. Wei, X.Q. Yang, X. Zeng, X.Z. Zhang*, Antibody engineered platelets attracted by bacteria-induced tumor-specifc blood coagulation for checkpoint inhibitor immunotherapy. Adv. Funct. Mater. 2021, 2009744.

10. J.X. Fan, M.T. Niu, Y.T. Qin, Y.X. Sun, X.Z. Zhang*, Progress of engineered bacteria for tumor therapy. Adv. Drug Deliver. Rev. 2022, 185, 114296.

11. J.X. Fan‡, R.H. Deng‡, H. W., X.H. Liu, X.N. Wang, R. Qin, X. Jin, T.R. Lei, D.W. Zheng, P.H. Zhou, Y.X. Sun, X.Z. Zhang*, Epigenetics-based tumor cells pyroptosis for enhancing the immunological effect of chemotherapeutic nanocarriers. Nano Lett. 2019, 11, 8049-8058.

12. P. Pan‡, J.X. Fan‡, X.N. Wang, J.W. Wang, D.W. Zheng, H. Cheng, X.Z. Zhang*, Bio-orthogonal bacterial reactor for remission of heavy metal poisoning and ros elimination. Adv. Sci. 2019, 201902500.

13. J.X. Fan‡, Z.H. Li‡, X.H. Liu, D.W. Zheng, Y. Chen, X.Z. Zhang*, Bacteria-mediated tumor therapy utilizing photothermally controlled TNF‑α expression via oral administration. Nano Lett. 2018, 18, 2373.

14. J.X. Fan‡, D.W. Zheng‡, L. Rong, J.Y. Zhu, S. Hong, C. Li, Z.S. Xu, S.X. Cheng, X.Z. Zhang*, Targeting epithelial-mesenchymal transition: Metal organic network nano-complexes for preventing tumor metastasis, Biomaterials 2017, 139, 116-126.