常用链接
研究领域
-
1、病原微生物耐药性产生机制研究，从蛋白质相互作用和基因转录调控层面系统鉴定参与调控细菌耐药性产生的新型转录因子和信号通路。
2、合成生物学研究，从代谢调控，代谢网络重构层面着手，以酵母和芽孢杆菌等做底盘，生产生物基材料和仿生超材料。
论文成果 MORE+
- · Dehydroquinate synthase DHQS directly binds to streptomycin and regulates resistance of Mycobacterium bovis to streptomycin in a non-canonical mode.Frontiers in Microbiology.2022,13
- · 1. Yang,M., Jia,S.-H., Tao,H.-L., Zhu,C., Jia,W.-Z., Hu,L.-H. and Gao,C.-H.* (2020) Cd(II)-binding transcriptional regulator interacts with isoniazid and regulates drug susceptibility in mycobacteria.
- · 2. Yang M#, Zhang L#, Tao H-L#, Sun Y-C, Lou Z-Z, Jia W-Z, Hu L-H, Gao C-H*(2019) OxiR specifically responds to isoniazid and regulates isoniazid susceptibility in mycobacteria. FEMS Microbiol Lett. 3
- · 3. Gao C-H, Wei W-P, Tao H-L, Cai L-K, Jia W-Z, Hu L, Yang M*(2019). Cross-talk between the three furA orthologs in Mycobacterium smegmatis and the contribution to isoniazid resistance. J Biochem. 166
专利
- 暂无内容
著作成果
- 暂无内容