Scientific Research
Research Field
-
Regulatory mechanism of drug resistance in mycobacteria
Mechanism of metabolism regulation of oil-producing yeast
Paper Publications
more+- [1] Dehydroquinate synthase DHQS directly binds to streptomycin and regulates resistance of Mycobacterium bovis to streptomycin in a non-canonical mode .Frontiers in Microbiology .2022 ,13
- [2] 1. Yang,M., Jia,S.-H., Tao,H.-L., Zhu,C., Jia,W.-Z., Hu,L.-H. and Gao,C.-H.* (2020) Cd(II)-binding transcriptional regulator interacts with isoniazid and regulates drug susceptibility in mycobacteria. J Biochem, 10.1093/jb/mvaa086.
- [3] 2. Yang M#, Zhang L#, Tao H-L#, Sun Y-C, Lou Z-Z, Jia W-Z, Hu L-H, Gao C-H*(2019) OxiR specifically responds to isoniazid and regulates isoniazid susceptibility in mycobacteria. FEMS Microbiol Lett. 366(10): fnz109.
- [4] 3. Gao C-H, Wei W-P, Tao H-L, Cai L-K, Jia W-Z, Hu L, Yang M*(2019). Cross-talk between the three furA orthologs in Mycobacterium smegmatis and the contribution to isoniazid resistance. J Biochem. 166(3): 237-243.
- [5] 4. Zhu C, Liu Y, Hu L-H, Yang M*, He Z-G*(2018) Molecular mechanism of the synergistic activity of ethambutol and isoniazid against Mycobacterium tuberculosis. J. Biol. Chem. 293(43): 16741-16750.
Patents
- No content
Published Books
- No content
Research Projects
more+- [1] (8) 国家自然科学基金面上项目(32070079),58万,2020/01-2024/12,主持,在研
- [2] (7)国家自然科学基金重点项目(31730005),260万元(承担子课题30万) 2018/01-2022/12,参与,在研;
- [3] (6)湖北省自然科学基金面上项目(2018CFB495),5万 2018/01-2020/12,
- [4] (5)兰州兽医研究所家畜疫病病原生物学国家重点实验室2016年度开放课题(SKLVEB2016KFKT008),10万元 , 2017/07-2019/07,主持
- [5] (4)中央高校基本业务费(2662016QD007),20万, 2016/01-2018/12,项目主持人
Copyright © 2017 Huazhong University of Science & Technology