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1. 基于大型前瞻性队列研究，探讨环境因素（包括营养、生活方式、膳食来源为主的环境污染物等）和遗传因素，以及二者交互作用与肥胖、2型糖尿病、心脑血管疾病等发生发展的关系，建 立早期预测模型；
2. 利用多组学和系统流行病学的方法，探讨2型糖尿病、心脑血管疾病等发生发展的机制，寻找潜在的干预靶点；
3. 膳食营养干预研究；
- Associations of Combined Healthy Lifestyle Factors with Risks of Diabetes, Cardiovascular Disease, Cancer, and Mortality Among Adults with Prediabetes: Four Prospective Cohort Studies in China, the United Kingdom, and the United States..Engineering,
- Associations of combined healthy lifestyles with cancer morbidity and mortality among individuals with diabetes: results from five cohort studies in the US, the UK, and China.Diabetologia,
- Association between serum 25-hydroxy vitamin D concentrations and mortality among individuals with metabolic dysfunction-associated fatty liver disease: a prospective cohort study..Am J Clin Nutr,
- Vitamin D Status, Genetic Factors, and Risk of Cardiovascular Disease among Individuals with Type 2 Diabetes: A Prospective Study..Am J Clin Nutr,
- Associations of Serum Carotenoids With Risk of Cardiovascular Mortality Among Individuals With Type 2 Diabetes: Results From NHANES..Diabetes Care,
- Associations of New-onset Atrial Fibrillation with Risks of Cardiovascular Disease, Chronic Kidney Disease and Mortality among Patients with Type 2 Diabetes..Diabetes Care,
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